Find the Blacknet terminal and interact with it (B button), watching out for viral detectors.
An exact location of Dr. David Castleman is [197, 1003].
After reaching the first group of scientists, shapeshift, so you could approach them.
you’ve got the option to now go to the second group of scientists.
In this case I recommend aggressive option, unless you do not mind a very slow elimination of guards.
After that, go again to location [258, 953].
Interact with the terminal again (B button).
check that that lieutenant is not observed by anyone and consume him (button B and button Y).
After a short cut-scene, go to the lair in location [290, 1266].
Once again you should enter the zone inaccessible for civilians, disguised as a soldier or a scientist.
Stand in the shiny circle (screen above) and press B button to get into the lair.
you might also consume these soldiers, thus regenerating yourself.
Fight until both vehicles are destroyed.
Grab him and consume him (B button and Y button).
Notice, that for completing the mission you were rewarded with possibility of choosing mutation from Locomotion category.
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